HCSGD entry for FES

1. General information

Official gene symbolFES
Entrez ID2242
Gene full namefeline sarcoma oncogene
Other gene symbolsFPS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004713Protein tyrosine kinase activityIDA IEAmolecular_function
GO:0004715Non-membrane spanning protein tyrosine kinase activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005925Focal adhesionIDAcellular_component
GO:0006468Protein phosphorylationTASbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0008360Regulation of cell shapeIMPbiological_process
GO:0010976Positive regulation of neuron projection developmentIMPbiological_process
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0016023Cytoplasmic membrane-bounded vesicleIEAcellular_component
GO:0018108Peptidyl-tyrosine phosphorylationIDAbiological_process
GO:0030155Regulation of cell adhesionIMPbiological_process
GO:0031116Positive regulation of microtubule polymerizationIMPbiological_process
GO:0031234Extrinsic component of cytoplasmic side of plasma membraneIDAcellular_component
GO:0031410Cytoplasmic vesicleIDAcellular_component
GO:0034987Immunoglobulin receptor bindingIDAmolecular_function
GO:0035091Phosphatidylinositol bindingIDAmolecular_function
GO:0042127Regulation of cell proliferationIMPbiological_process
GO:0043304Regulation of mast cell degranulationIMPbiological_process
GO:0045595Regulation of cell differentiationIMPbiological_process
GO:0045639Positive regulation of myeloid cell differentiationIMPbiological_process
GO:0046777Protein autophosphorylationIDAbiological_process
GO:0060627Regulation of vesicle-mediated transportTASbiological_process
GO:2000145Regulation of cell motilityIMPbiological_process
GO:2000251Positive regulation of actin cytoskeleton reorganizationIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92172892750.14094760840.99999024730.7219073750

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1619183694
GSE13712_SHEARDown-0.1552018612
GSE13712_STATICDown-0.3718377236
GSE19018Up0.2054886551
GSE19899_A1Down-0.1395989187
GSE19899_A2Down-0.2805943981
PubMed_21979375_A1Down-0.4461202102
PubMed_21979375_A2Down-0.2493975533
GSE35957Down-0.3931445640
GSE36640Down-0.1539177975
GSE54402Down-0.0557414540
GSE9593Down-0.1759989056
GSE43922Up0.0159413952
GSE24585Up0.2638466098
GSE37065Down-0.0714712036
GSE28863_A1Down-0.0458417174
GSE28863_A2Down-0.2444512735
GSE28863_A3Up0.2249363546
GSE28863_A4Up0.0758690996
GSE48662Down-0.1521398745

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029960MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.