HCSGD entry for FKBP3
1. General information
| Official gene symbol | FKBP3 |
|---|---|
| Entrez ID | 2287 |
| Gene full name | FK506 binding protein 3, 25kDa |
| Other gene symbols | FKBP-25 FKBP-3 FKBP25 PPIase |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000413 | Protein peptidyl-prolyl isomerization | IBA | biological_process |
| GO:0003755 | Peptidyl-prolyl cis-trans isomerase activity | IBA | molecular_function |
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005528 | FK506 binding | IBA | molecular_function |
| GO:0005634 | Nucleus | IBA | cellular_component |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0016020 | Membrane | IBA | cellular_component |
| GO:0018208 | Peptidyl-proline modification | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9051512443 | 0.2033762737 | 0.9999902473 | 0.8735262196 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0516780863 |
| GSE13712_SHEAR | Up | 0.0335905367 |
| GSE13712_STATIC | Up | 0.0983062573 |
| GSE19018 | Down | -0.0447400919 |
| GSE19899_A1 | Down | -0.1093314358 |
| GSE19899_A2 | Up | 0.0521903161 |
| PubMed_21979375_A1 | Down | -0.0231487963 |
| PubMed_21979375_A2 | Down | -0.3626703696 |
| GSE35957 | Down | -0.1434049545 |
| GSE36640 | Down | -0.0547517616 |
| GSE54402 | Up | 0.0719765584 |
| GSE9593 | Down | -0.1915598299 |
| GSE43922 | Down | -0.6009749282 |
| GSE24585 | Up | 0.0902321469 |
| GSE37065 | Down | -0.1627343495 |
| GSE28863_A1 | Up | 0.0232997716 |
| GSE28863_A2 | Up | 0.1749139439 |
| GSE28863_A3 | Up | 0.1503768075 |
| GSE28863_A4 | Up | 0.1809209493 |
| GSE48662 | Down | -0.6189137394 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT021002 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027824 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038728 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
