HCSGD entry for RPIA
1. General information
| Official gene symbol | RPIA |
|---|---|
| Entrez ID | 22934 |
| Gene full name | ribose 5-phosphate isomerase A |
| Other gene symbols | RPI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004751 | Ribose-5-phosphate isomerase activity | NAS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006098 | Pentose-phosphate shunt | TAS | biological_process |
| GO:0009052 | Pentose-phosphate shunt, non-oxidative branch | IEA | biological_process |
| GO:0019693 | Ribose phosphate metabolic process | IEA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0048029 | Monosaccharide binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9737977205 | 0.0203014703 | 0.9999902473 | 0.2761191632 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2743030771 |
| GSE13712_SHEAR | Down | -0.2556098686 |
| GSE13712_STATIC | Up | 0.1061712250 |
| GSE19018 | Down | -0.5362323682 |
| GSE19899_A1 | Down | -0.4788894322 |
| GSE19899_A2 | Up | 0.1009947260 |
| PubMed_21979375_A1 | Up | 0.0205260164 |
| PubMed_21979375_A2 | Down | -0.6481455373 |
| GSE35957 | Down | -0.3012886670 |
| GSE36640 | Down | -0.9767187371 |
| GSE54402 | Up | 0.0384797822 |
| GSE9593 | Down | -0.5770653178 |
| GSE43922 | Up | 0.0442137755 |
| GSE24585 | Down | -0.4403529929 |
| GSE37065 | Down | -0.0042540112 |
| GSE28863_A1 | Down | -0.3108371991 |
| GSE28863_A2 | Down | -0.0105475456 |
| GSE28863_A3 | Down | -0.5435806104 |
| GSE28863_A4 | Up | 0.0093591850 |
| GSE48662 | Up | 0.1266564402 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| D-4-Phosphoerythronic Acid | DB01756 | EXPT01163 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT001851 | Luciferase reporter assay//Reporter assay;Other | Non-Functional MTI | 15131085 |
| hsa-miR-373-3p | MIMAT0000726 | MIRT002559 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019459 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022847 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025226 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-30e-5p | MIMAT0000692 | MIRT044134 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-191-5p | MIMAT0000440 | MIRT045816 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | NA | hsa-miR-373 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
