HCSGD entry for ZHX3
1. General information
| Official gene symbol | ZHX3 |
|---|---|
| Entrez ID | 23051 |
| Gene full name | zinc fingers and homeoboxes 3 |
| Other gene symbols | TIX1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA IEA | molecular_function |
| GO:0003714 | Transcription corepressor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045669 | Positive regulation of osteoblast differentiation | IMP | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2168997189 | 0.1003386080 | 0.8956794795 | 0.6072689124 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1636998795 |
| GSE13712_SHEAR | Down | -0.3266243311 |
| GSE13712_STATIC | Down | -0.3250386396 |
| GSE19018 | Up | 0.0406553704 |
| GSE19899_A1 | Down | -0.0589747925 |
| GSE19899_A2 | Down | -0.2649085602 |
| PubMed_21979375_A1 | Down | -1.8720191998 |
| PubMed_21979375_A2 | Down | -0.6012219704 |
| GSE35957 | Up | 0.4211735710 |
| GSE36640 | Up | 0.3312790410 |
| GSE54402 | Down | -0.4924014547 |
| GSE9593 | Up | 0.5479698830 |
| GSE43922 | Down | -0.4869722782 |
| GSE24585 | Down | -0.0497542403 |
| GSE37065 | Down | -0.3705366704 |
| GSE28863_A1 | Up | 1.0390493176 |
| GSE28863_A2 | Up | 1.1180770852 |
| GSE28863_A3 | Down | -0.0055054615 |
| GSE28863_A4 | Up | 0.0166298181 |
| GSE48662 | Up | 0.4929826387 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022152 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037094 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
