HCSGD entry for FLII
1. General information
| Official gene symbol | FLII |
|---|---|
| Entrez ID | 2314 |
| Gene full name | flightless I homolog (Drosophila) |
| Other gene symbols | FLI FLIL Fli1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005925 | Focal adhesion | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006936 | Muscle contraction | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1463757950 | 0.6172853729 | 0.7667120700 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2245745725 |
| GSE13712_SHEAR | Down | -0.1664968239 |
| GSE13712_STATIC | Down | -0.0813569124 |
| GSE19018 | Up | 0.2355221619 |
| GSE19899_A1 | Down | -0.5580728050 |
| GSE19899_A2 | Up | 0.1218854651 |
| PubMed_21979375_A1 | Up | 0.1594962723 |
| PubMed_21979375_A2 | Up | 0.2856394470 |
| GSE35957 | Down | -0.2276630887 |
| GSE36640 | Down | -0.0046850928 |
| GSE54402 | Down | -0.0170394290 |
| GSE9593 | Up | 0.2926381254 |
| GSE43922 | Down | -0.1363073978 |
| GSE24585 | Down | -0.0612281783 |
| GSE37065 | Down | -0.0563286964 |
| GSE28863_A1 | Up | 0.8980192780 |
| GSE28863_A2 | Up | 0.5654484790 |
| GSE28863_A3 | Up | 0.1502028826 |
| GSE28863_A4 | Up | 0.0678645355 |
| GSE48662 | Down | -0.3011541745 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022789 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-484 | MIMAT0002174 | MIRT041743 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042489 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043515 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT048726 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052017 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
