HCSGD entry for FLNC
1. General information
| Official gene symbol | FLNC |
|---|---|
| Entrez ID | 2318 |
| Gene full name | filamin C, gamma |
| Other gene symbols | ABP-280 ABP280A ABPA ABPL FLN2 MFM5 MPD4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0008092 | Cytoskeletal protein binding | IPI | molecular_function |
| GO:0016528 | Sarcoplasm | IEA | cellular_component |
| GO:0030018 | Z disc | IEA | cellular_component |
| GO:0030506 | Ankyrin binding | IPI | molecular_function |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0042383 | Sarcolemma | IDA | cellular_component |
| GO:0043034 | Costamere | TAS | cellular_component |
| GO:0048747 | Muscle fiber development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0373087573 | 0.1217092056 | 0.4364015514 | 0.6700246028 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3321641762 |
| GSE13712_SHEAR | Up | 0.3755047025 |
| GSE13712_STATIC | Up | 0.6579107749 |
| GSE19018 | Up | 0.6448985853 |
| GSE19899_A1 | Down | -0.7279960010 |
| GSE19899_A2 | Down | -1.3706699074 |
| PubMed_21979375_A1 | Down | -0.0292230028 |
| PubMed_21979375_A2 | Down | -0.2648442870 |
| GSE35957 | Up | 0.8756154253 |
| GSE36640 | Up | 0.5156267796 |
| GSE54402 | Down | -0.3108929045 |
| GSE9593 | Up | 0.3379382766 |
| GSE43922 | Down | -0.2494112397 |
| GSE24585 | Up | 0.1819802593 |
| GSE37065 | Down | -0.4566096999 |
| GSE28863_A1 | Up | 0.6197195956 |
| GSE28863_A2 | Up | 0.7625294127 |
| GSE28863_A3 | Up | 0.0632658779 |
| GSE28863_A4 | Down | -0.3741043909 |
| GSE48662 | Up | 0.7248557454 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT024106 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-454-3p | MIMAT0003885 | MIRT039242 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
