HCSGD entry for ARHGEF9

1. General information

Official gene symbolARHGEF9
Entrez ID23229
Gene full nameCdc42 guanine nucleotide exchange factor (GEF) 9
Other gene symbolsCOLLYBISTIN EIEE8 HPEM-2 PEM-2 PEM2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0034220Ion transmembrane transportTASbiological_process
GO:0043065Positive regulation of apoptotic processTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.36168568440.13525856160.99999024730.7095134887

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0747397221
GSE13712_SHEARDown-0.5239020646
GSE13712_STATICUp0.0204194135
GSE19018Up0.0068031797
GSE19899_A1Up0.0121102297
GSE19899_A2Down-0.1745671226
PubMed_21979375_A1Down-1.8078559700
PubMed_21979375_A2Up0.2027136344
GSE35957Up0.5201490997
GSE36640Up0.9985526253
GSE54402Down-0.6946617600
GSE9593Up0.1406927785
GSE43922Down-0.5288475350
GSE24585Up0.4452094042
GSE37065Down-0.1322774818
GSE28863_A1Down-0.1448347721
GSE28863_A2Up0.3615190891
GSE28863_A3Down-0.2992748136
GSE28863_A4Up0.1516313721
GSE48662Up0.0171448563

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.