HCSGD entry for NCS1


1. General information

Official gene symbolNCS1
Entrez ID23413
Gene full nameneuronal calcium sensor 1
Other gene symbolsFLUP FREQ
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIEAmolecular_function
GO:0005245Voltage-gated calcium channel activityISSmolecular_function
GO:0005509Calcium ion bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006810TransportISSbiological_process
GO:0006812Cation transportISSbiological_process
GO:0010975Regulation of neuron projection developmentISSbiological_process
GO:0014069Postsynaptic densityIEAcellular_component
GO:0019901Protein kinase bindingIEAmolecular_function
GO:0030001Metal ion transportISSbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0030424AxonIEAcellular_component
GO:0030425DendriteIEAcellular_component
GO:0031410Cytoplasmic vesicleIEAcellular_component
GO:0032580Golgi cisterna membraneIEAcellular_component
GO:0034220Ion transmembrane transportISSbiological_process
GO:0034765Regulation of ion transmembrane transportISSbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0045921Positive regulation of exocytosisIEAbiological_process
GO:0048015Phosphatidylinositol-mediated signalingIEAbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0055085Transmembrane transportISSbiological_process
GO:0070588Calcium ion transmembrane transportISSbiological_process
GO:0072511Divalent inorganic cation transportISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38189599560.11012679610.99999024730.6353416831

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1757949405
GSE13712_SHEARUp0.1241562698
GSE13712_STATICUp0.1347778452
GSE19018Down-0.1269481353
GSE19899_A1Down-0.1800242451
GSE19899_A2Up0.5273813646
PubMed_21979375_A1Down-0.1188326829
PubMed_21979375_A2Up0.4216449885
GSE35957Down-0.3333750224
GSE36640Down-0.1641412622
GSE54402Up0.6726658957
GSE9593Up0.1103304388
GSE43922Up0.0045867434
GSE24585Down-0.7348698928
GSE37065Down-0.2129216095
GSE28863_A1Down-0.4694436381
GSE28863_A2Down-0.2789989394
GSE28863_A3Down-0.2653032569
GSE28863_A4Up0.0683498178
GSE48662Up0.2423581983

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019373MicroarrayFunctional MTI (Weak)17612493
hsa-miR-132-3pMIMAT0000426MIRT021815MicroarrayFunctional MTI (Weak)17612493
hsa-miR-1MIMAT0000416MIRT023761ProteomicsFunctional MTI (Weak)18668040
hsa-miR-744-5pMIMAT0004945MIRT037529CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT042108CLASHFunctional MTI (Weak)23622248
hsa-miR-331-3pMIMAT0000760MIRT043430CLASHFunctional MTI (Weak)23622248
hsa-miR-330-3pMIMAT0000751MIRT043837CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.