HCSGD entry for SEC11A
1. General information
| Official gene symbol | SEC11A |
|---|---|
| Entrez ID | 23478 |
| Gene full name | SEC11 homolog A (S. cerevisiae) |
| Other gene symbols | 1810012E07Rik SEC11L1 SPC18 SPCS4A sid2895 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006465 | Signal peptide processing | IEA | biological_process |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0008236 | Serine-type peptidase activity | IEA | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0050796 | Regulation of insulin secretion | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9621841647 | 0.1670058926 | 0.9999902473 | 0.7898943576 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1342303699 |
| GSE13712_SHEAR | Down | -0.1583626080 |
| GSE13712_STATIC | Down | -0.2010826125 |
| GSE19018 | Down | -0.2128843968 |
| GSE19899_A1 | Down | -0.1527208550 |
| GSE19899_A2 | Down | -0.2936278327 |
| PubMed_21979375_A1 | Down | -0.2362891145 |
| PubMed_21979375_A2 | Down | -0.4303468105 |
| GSE35957 | Down | -0.0400455471 |
| GSE36640 | Down | -0.0269507413 |
| GSE54402 | Down | -0.0363840596 |
| GSE9593 | Down | -0.0520738104 |
| GSE43922 | Up | 0.0381177799 |
| GSE24585 | Up | 0.1260558654 |
| GSE37065 | Down | -0.1811952595 |
| GSE28863_A1 | Up | 0.0861174807 |
| GSE28863_A2 | Down | -0.0701425885 |
| GSE28863_A3 | Down | -0.3548571124 |
| GSE28863_A4 | Up | 0.2452571364 |
| GSE48662 | Down | -0.3248310119 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT004120 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT004120 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028396 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031376 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032228 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT041796 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
