HCSGD entry for MAPK8IP2

1. General information

Official gene symbolMAPK8IP2
Entrez ID23542
Gene full namemitogen-activated protein kinase 8 interacting protein 2
Other gene symbolsIB2 JIP2 PRKM8IPL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000165MAPK cascadeIDAbiological_process
GO:0001540Beta-amyloid bindingNASmolecular_function
GO:0001662Behavioral fear responseIEA ISSbiological_process
GO:0005078MAP-kinase scaffold activityNASmolecular_function
GO:0005198Structural molecule activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0007172Signal complex assemblyTASbiological_process
GO:0007254JNK cascadeIEAbiological_process
GO:0007617Mating behaviorIEAbiological_process
GO:0009967Positive regulation of signal transductionNASbiological_process
GO:0010469Regulation of receptor activityISSbiological_process
GO:0019894Kinesin bindingIEA ISSmolecular_function
GO:0019901Protein kinase bindingIPImolecular_function
GO:0030295Protein kinase activator activityIDA IGImolecular_function
GO:0032403Protein complex bindingIEAmolecular_function
GO:0032874Positive regulation of stress-activated MAPK cascadeIEAbiological_process
GO:0035176Social behaviorIEA ISSbiological_process
GO:0042325Regulation of phosphorylationIDA IGIbiological_process
GO:0042327Positive regulation of phosphorylationIDA IGIbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043085Positive regulation of catalytic activityIDA IGIbiological_process
GO:0043234Protein complexIEAcellular_component
GO:0045859Regulation of protein kinase activityIDA IGIbiological_process
GO:0045860Positive regulation of protein kinase activityIDA IGIbiological_process
GO:0046328Regulation of JNK cascadeIDAbiological_process
GO:0046958Nonassociative learningIEA ISSbiological_process
GO:0048813Dendrite morphogenesisIEA ISSbiological_process
GO:0050790Regulation of catalytic activityIDA IGIbiological_process
GO:0051966Regulation of synaptic transmission, glutamatergicIEA ISSbiological_process
GO:0060079Regulation of excitatory postsynaptic membrane potentialIEA ISSbiological_process
GO:0097481Neuronal postsynaptic densityIEA ISScellular_component
GO:2000310Regulation of N-methyl-D-aspartate selective glutamate receptor activityIEA ISSbiological_process
GO:2000311Regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activityIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62742395050.85387331790.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1106299672
GSE13712_SHEARUp0.0273361311
GSE13712_STATICDown-0.0226179859
GSE19018Up0.0102592163
GSE19899_A1Down-0.1292560889
GSE19899_A2Up0.2321377062
PubMed_21979375_A1Down-0.2112334557
PubMed_21979375_A2Down-0.0374700402
GSE35957Up0.0104643038
GSE36640Up0.0597626041
GSE54402Up0.0027456867
GSE9593Up0.0833593668
GSE43922Up0.0424087095
GSE24585Up0.0748948156
GSE37065Up0.0190688029
GSE28863_A1Down-0.1112071783
GSE28863_A2Up0.1556366013
GSE28863_A3Up0.3945086438
GSE28863_A4Up0.0499288039
GSE48662Up0.0854389291

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-296-3pMIMAT0004679MIRT038432CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.