HCSGD entry for SHPK
1. General information
| Official gene symbol | SHPK |
|---|---|
| Entrez ID | 23729 |
| Gene full name | sedoheptulokinase |
| Other gene symbols | CARKL SHK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | IDA | biological_process |
| GO:0009052 | Pentose-phosphate shunt, non-oxidative branch | ISS | biological_process |
| GO:0016310 | Phosphorylation | IDA | biological_process |
| GO:0035963 | Cellular response to interleukin-13 | ISS | biological_process |
| GO:0043030 | Regulation of macrophage activation | ISS | biological_process |
| GO:0050277 | Sedoheptulokinase activity | IDA | molecular_function |
| GO:0050727 | Regulation of inflammatory response | ISS | biological_process |
| GO:0071222 | Cellular response to lipopolysaccharide | IDA | biological_process |
| GO:0071353 | Cellular response to interleukin-4 | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2797811063 | 0.4920144485 | 0.9765440260 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2364771669 |
| GSE13712_SHEAR | Down | -0.4925108151 |
| GSE13712_STATIC | Down | -0.2451899670 |
| GSE19018 | Down | -0.0862054570 |
| GSE19899_A1 | Up | 0.0957382863 |
| GSE19899_A2 | Up | 0.2488770284 |
| PubMed_21979375_A1 | Up | 1.3113395224 |
| PubMed_21979375_A2 | Up | 0.4226146071 |
| GSE35957 | Down | -0.0295738923 |
| GSE36640 | Down | -0.8065760511 |
| GSE54402 | Up | 0.5890567237 |
| GSE9593 | Down | -0.5217961948 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.2506594165 |
| GSE28863_A2 | Up | 0.2086249527 |
| GSE28863_A3 | Down | -0.1212271608 |
| GSE28863_A4 | Up | 0.0901627012 |
| GSE48662 | Down | -0.3576660517 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022509 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039817 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
