HCSGD entry for GABRA6

1. General information

Official gene symbolGABRA6
Entrez ID2559
Gene full namegamma-aminobutyric acid (GABA) A receptor, alpha 6
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004890GABA-A receptor activityIEAmolecular_function
GO:0005230Extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0005254Chloride channel activityIEAmolecular_function
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0006821Chloride transportIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007214Gamma-aminobutyric acid signaling pathwayIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008503Benzodiazepine receptor activityTASmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0045202SynapseIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.48717565060.86204617610.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0188487903
GSE13712_SHEARUp0.0450832720
GSE13712_STATICDown-0.0827664589
GSE19018Up0.1723539031
GSE19899_A1Up0.2995071594
GSE19899_A2Up0.1876377953
PubMed_21979375_A1Up0.1583203956
PubMed_21979375_A2Up0.0767525963
GSE35957Down-0.0423729907
GSE36640Up0.0461728577
GSE54402Down-0.0312256288
GSE9593Up0.0121225786
GSE43922Up0.0157653252
GSE24585Down-0.0639741261
GSE37065Down-0.0273236300
GSE28863_A1Up0.1420916744
GSE28863_A2Up0.0831344538
GSE28863_A3Up0.1395998197
GSE28863_A4Down-0.1498597446
GSE48662Up0.0538158683

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.