HCSGD entry for GABRB2

1. General information

Official gene symbolGABRB2
Entrez ID2561
Gene full namegamma-aminobutyric acid (GABA) A receptor, beta 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004890GABA-A receptor activityIEA ISSmolecular_function
GO:0005230Extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0005237Inhibitory extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0005254Chloride channel activityIEAmolecular_function
GO:0005829CytosolIEAcellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0007214Gamma-aminobutyric acid signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007605Sensory perception of soundIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0043524Negative regulation of neuron apoptotic processIEAbiological_process
GO:0045202SynapseIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0051932Synaptic transmission, GABAergicISSbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0060119Inner ear receptor cell developmentIEAbiological_process
GO:0060384InnervationIEAbiological_process
GO:0090102Cochlea developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86907628130.79836256980.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0139723543
GSE13712_SHEARDown-0.0440630861
GSE13712_STATICUp0.0525970109
GSE19018Up0.0612231303
GSE19899_A1Up0.1294683900
GSE19899_A2Up0.0109296863
PubMed_21979375_A1Down-0.1605878319
PubMed_21979375_A2Down-0.0967379421
GSE35957Up0.0067322119
GSE36640Up0.0230621556
GSE54402Down-0.0037784269
GSE9593Up0.0139070186
GSE43922Up0.0181621042
GSE24585Down-0.0387884498
GSE37065Down-0.0427012676
GSE28863_A1Down-0.0950042687
GSE28863_A2Up0.1884130008
GSE28863_A3Up0.1950027791
GSE28863_A4Down-0.0781220598
GSE48662Down-0.0408570523

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.