HCSGD entry for GABRB3
1. General information
| Official gene symbol | GABRB3 |
|---|---|
| Entrez ID | 2562 |
| Gene full name | gamma-aminobutyric acid (GABA) A receptor, beta 3 |
| Other gene symbols | ECA5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004890 | GABA-A receptor activity | IEA | molecular_function |
| GO:0005230 | Extracellular ligand-gated ion channel activity | IEA | molecular_function |
| GO:0005254 | Chloride channel activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006811 | Ion transport | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007605 | Sensory perception of sound | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0034707 | Chloride channel complex | IEA | cellular_component |
| GO:0043524 | Negative regulation of neuron apoptotic process | IEA | biological_process |
| GO:0045202 | Synapse | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0060119 | Inner ear receptor cell development | IEA | biological_process |
| GO:0060384 | Innervation | IEA | biological_process |
| GO:0090102 | Cochlea development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8286069222 | 0.5725846358 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0512395492 |
| GSE13712_SHEAR | Down | -0.1348443266 |
| GSE13712_STATIC | Up | 0.0230552069 |
| GSE19018 | Up | 0.0110389423 |
| GSE19899_A1 | Down | -0.0548917648 |
| GSE19899_A2 | Down | -0.0236454928 |
| PubMed_21979375_A1 | Up | 0.0339333548 |
| PubMed_21979375_A2 | Down | -0.0196014642 |
| GSE35957 | Down | -0.1228348290 |
| GSE36640 | Down | -0.1021261445 |
| GSE54402 | Up | 0.0792372600 |
| GSE9593 | Up | 0.0183547969 |
| GSE43922 | Up | 0.0623007999 |
| GSE24585 | Down | -0.2550945505 |
| GSE37065 | Up | 0.0411671442 |
| GSE28863_A1 | Up | 0.1181982316 |
| GSE28863_A2 | Down | -0.3516393593 |
| GSE28863_A3 | Up | 0.3764117848 |
| GSE28863_A4 | Up | 0.0423116165 |
| GSE48662 | Down | -0.0145811124 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029728 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045964 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
