HCSGD entry for GAD2

1. General information

Official gene symbolGAD2
Entrez ID2572
Gene full nameglutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Other gene symbolsGAD65
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIEAcellular_component
GO:0004351Glutamate decarboxylase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006540Glutamate decarboxylation to succinateIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007269Neurotransmitter secretionTASbiological_process
GO:0016595Glutamate bindingIEAmolecular_function
GO:0016831Carboxy-lyase activityIEAmolecular_function
GO:0019752Carboxylic acid metabolic processIEAbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0030170Pyridoxal phosphate bindingIEAmolecular_function
GO:0030424AxonIEAcellular_component
GO:0030672Synaptic vesicle membraneIEAcellular_component
GO:0031225Anchored component of membraneIEAcellular_component
GO:0042136Neurotransmitter biosynthetic processIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042734Presynaptic membraneIEAcellular_component
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0061202Clathrin-sculpted gamma-aminobutyric acid transport vesicle membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87133531780.82991956610.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0534174163
GSE13712_SHEARDown-0.0881256327
GSE13712_STATICDown-0.0304946564
GSE19018Up0.0041011218
GSE19899_A1Up0.0454729712
GSE19899_A2Up0.0425733020
PubMed_21979375_A1Up0.1182333723
PubMed_21979375_A2Down-0.1082832973
GSE35957Up0.1358182302
GSE36640Up0.0054652597
GSE54402Up0.0129019515
GSE9593Down-0.0042873986
GSE43922Up0.0146693892
GSE24585Down-0.0749382144
GSE37065Up0.0066016484
GSE28863_A1Down-0.0758767954
GSE28863_A2Down-0.0377403619
GSE28863_A3Up0.2293925976
GSE28863_A4Up0.0945623154
GSE48662Up0.0280991620

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.