HCSGD entry for ZNF385A

1. General information

Official gene symbolZNF385A
Entrez ID25946
Gene full namezinc finger protein 385A
Other gene symbolsHZF RZF ZFP385 ZNF385
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000790Nuclear chromatinIDAcellular_component
GO:0002039P53 bindingIPImolecular_function
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0003730MRNA 3'-UTR bindingIEA ISSmolecular_function
GO:0005730NucleolusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006915Apoptotic processIEA ISSbiological_process
GO:0006974Cellular response to DNA damage stimulusIEA ISSbiological_process
GO:0007599HemostasisIEAbiological_process
GO:0007611Learning or memoryIEAbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0010609MRNA localization resulting in posttranscriptional regulation of gene expressionIEA ISSbiological_process
GO:0030220Platelet formationIEAbiological_process
GO:0030425DendriteIEA ISScellular_component
GO:0035855Megakaryocyte developmentISSbiological_process
GO:0043025Neuronal cell bodyIEA ISScellular_component
GO:0045600Positive regulation of fat cell differentiationIEA ISSbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0070889Platelet alpha granule organizationIEAbiological_process
GO:1902164Positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorIMPbiological_process
GO:1902166Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorIMPbiological_process
GO:2000765Regulation of cytoplasmic translationIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01588528550.94192574370.31156229511.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0933313553
GSE13712_SHEARDown-0.6562412417
GSE13712_STATICDown-0.2280800061
GSE19018Up0.0411253834
GSE19899_A1Up0.1030469079
GSE19899_A2Up1.0333300319
PubMed_21979375_A1Up0.7752672547
PubMed_21979375_A2Up1.4326892643
GSE35957Down-0.3226950079
GSE36640Up0.0655584827
GSE54402Up0.1990533136
GSE9593Up0.0511928384
GSE43922Up0.5320015797
GSE24585Up0.3860771758
GSE37065Up0.3674494020
GSE28863_A1Up0.0132501631
GSE28863_A2Up0.1171043513
GSE28863_A3Up0.4409267694
GSE28863_A4Up0.1168136699
GSE48662Up0.2989072216

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-186-5pMIMAT0000456MIRT021123SequencingFunctional MTI (Weak)20371350
hsa-miR-149-5pMIMAT0000450MIRT045655CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.