HCSGD entry for PLEKHG3
1. General information
| Official gene symbol | PLEKHG3 |
|---|---|
| Entrez ID | 26030 |
| Gene full name | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| Other gene symbols | ARHGEF43 KIAA0599 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | molecular_function |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8243445044 | 0.6878321188 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0169722542 |
| GSE13712_SHEAR | Up | 0.0721665169 |
| GSE13712_STATIC | Up | 0.1082927423 |
| GSE19018 | Up | 0.0999664536 |
| GSE19899_A1 | Up | 0.0446906237 |
| GSE19899_A2 | Down | -0.0323517206 |
| PubMed_21979375_A1 | Up | 0.1575903723 |
| PubMed_21979375_A2 | Up | 0.0192788549 |
| GSE35957 | Down | -0.0749240060 |
| GSE36640 | Down | -0.2208100824 |
| GSE54402 | Down | -0.0052357003 |
| GSE9593 | Up | 0.0339898632 |
| GSE43922 | Up | 0.0253425796 |
| GSE24585 | Down | -0.2845760462 |
| GSE37065 | Down | -0.1366906553 |
| GSE28863_A1 | Up | 0.0635563865 |
| GSE28863_A2 | Up | 0.0031817624 |
| GSE28863_A3 | Up | 0.0915382478 |
| GSE28863_A4 | Up | 0.0813508626 |
| GSE48662 | Down | -0.1475097429 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018105 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042767 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
