HCSGD entry for LTN1
1. General information
| Official gene symbol | LTN1 |
|---|---|
| Entrez ID | 26046 |
| Gene full name | listerin E3 ubiquitin protein ligase 1 |
| Other gene symbols | C21orf10 C21orf98 RNF160 ZNF294 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0051865 | Protein autoubiquitination | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0907922305 | 0.5941936211 | 0.6333133280 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0286020715 |
| GSE13712_SHEAR | Up | 0.1225409122 |
| GSE13712_STATIC | Up | 0.1486010156 |
| GSE19018 | Up | 0.3025793468 |
| GSE19899_A1 | Up | 0.0381766010 |
| GSE19899_A2 | Up | 0.0883965243 |
| PubMed_21979375_A1 | Up | 0.0618028400 |
| PubMed_21979375_A2 | Up | 0.4471910083 |
| GSE35957 | Up | 0.0716831344 |
| GSE36640 | Down | -0.3565176862 |
| GSE54402 | Up | 0.0774132728 |
| GSE9593 | Down | -0.3320803351 |
| GSE43922 | Up | 0.0409780444 |
| GSE24585 | Up | 0.1631564287 |
| GSE37065 | Up | 0.1129108322 |
| GSE28863_A1 | Up | 0.9558528983 |
| GSE28863_A2 | Up | 1.1445795987 |
| GSE28863_A3 | Down | -0.5187623305 |
| GSE28863_A4 | Up | 0.0537192570 |
| GSE48662 | Down | -0.8466726910 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005158 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018915 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT021041 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027323 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031239 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036814 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-454-3p | MIMAT0003885 | MIRT039228 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
