HCSGD entry for GBP2
1. General information
| Official gene symbol | GBP2 |
|---|---|
| Entrez ID | 2634 |
| Gene full name | guanylate binding protein 2, interferon-inducible |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0060333 | Interferon-gamma-mediated signaling pathway | TAS | biological_process |
| GO:0060337 | Type I interferon signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4587100908 | 0.0018229475 | 0.9999902473 | 0.0820201709 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.0949726334 |
| GSE13712_SHEAR | Down | -1.5722682154 |
| GSE13712_STATIC | Down | -0.5049369854 |
| GSE19018 | Down | -1.1664074333 |
| GSE19899_A1 | Down | -0.1268545649 |
| GSE19899_A2 | Down | -2.3099286138 |
| PubMed_21979375_A1 | Down | -1.1638509873 |
| PubMed_21979375_A2 | Down | -0.3336816074 |
| GSE35957 | Down | -0.3117756667 |
| GSE36640 | Up | 0.7386002632 |
| GSE54402 | Down | -1.3073240759 |
| GSE9593 | Down | -0.3029892830 |
| GSE43922 | Down | -0.0052937335 |
| GSE24585 | Up | 0.0397977574 |
| GSE37065 | Up | 1.1957208344 |
| GSE28863_A1 | Up | 0.5524870843 |
| GSE28863_A2 | Up | 0.7046740824 |
| GSE28863_A3 | Down | -0.6279591320 |
| GSE28863_A4 | Down | -0.1536061821 |
| GSE48662 | Up | 0.1481133694 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017798 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029407 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
