HCSGD entry for GCSH
1. General information
| Official gene symbol | GCSH |
|---|---|
| Entrez ID | 2653 |
| Gene full name | glycine cleavage system protein H (aminomethyl carrier) |
| Other gene symbols | GCE NKH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004047 | Aminomethyltransferase activity | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005960 | Glycine cleavage complex | IEA | cellular_component |
| GO:0006546 | Glycine catabolic process | IEA TAS | biological_process |
| GO:0019464 | Glycine decarboxylation via glycine cleavage system | IEA | biological_process |
| GO:0019899 | Enzyme binding | IEA | molecular_function |
| GO:0032259 | Methylation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9842566354 | 0.0994768018 | 0.9999902473 | 0.6038581411 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0245293511 |
| GSE13712_SHEAR | Down | -0.0052780556 |
| GSE13712_STATIC | Down | -0.0697077443 |
| GSE19018 | Down | -0.2423428897 |
| GSE19899_A1 | Down | -0.1141508342 |
| GSE19899_A2 | Down | -0.2829328409 |
| PubMed_21979375_A1 | Down | -0.0599156206 |
| PubMed_21979375_A2 | Down | -0.3347466763 |
| GSE35957 | Down | -0.4478115892 |
| GSE36640 | Down | -0.2842605272 |
| GSE54402 | Up | 0.0694142988 |
| GSE9593 | Down | -0.1139030769 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.2781874191 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glycine | DB00145 | NUTR00028 |
| 6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid | DB03187 | EXPT02450 |
| Dihydrolipoic Acid | DB03760 | EXPT02769 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-421 | MIMAT0003339 | MIRT039361 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
