HCSGD entry for BMP10

1. General information

Official gene symbolBMP10
Entrez ID27302
Gene full namebone morphogenetic protein 10
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005125Cytokine activityIEAmolecular_function
GO:0005179Hormone activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0007155Cell adhesionIEAbiological_process
GO:0007512Adult heart developmentISSbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0009986Cell surfaceIDAcellular_component
GO:0010596Negative regulation of endothelial cell migrationIDAbiological_process
GO:0010613Positive regulation of cardiac muscle hypertrophyIMPbiological_process
GO:0010614Negative regulation of cardiac muscle hypertrophyISSbiological_process
GO:0010862Positive regulation of pathway-restricted SMAD protein phosphorylationIDAbiological_process
GO:0014898Cardiac muscle hypertrophy in response to stressICbiological_process
GO:0030018Z discIDAcellular_component
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0030308Negative regulation of cell growthIDAbiological_process
GO:0030336Negative regulation of cell migrationIDAbiological_process
GO:0030509BMP signaling pathwayIDAbiological_process
GO:0032924Activin receptor signaling pathwayIDAbiological_process
GO:0033612Receptor serine/threonine kinase bindingIDAmolecular_function
GO:0045214Sarcomere organizationISSbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0055009Atrial cardiac muscle tissue morphogenesisISSbiological_process
GO:0055010Ventricular cardiac muscle tissue morphogenesisISSbiological_process
GO:0055015Ventricular cardiac muscle cell developmentISSbiological_process
GO:0055117Regulation of cardiac muscle contractionIMPbiological_process
GO:0060038Cardiac muscle cell proliferationISSbiological_process
GO:0060045Positive regulation of cardiac muscle cell proliferationISSbiological_process
GO:0060298Positive regulation of sarcomere organizationIDAbiological_process
GO:0060347Heart trabecula formationISSbiological_process
GO:0060389Pathway-restricted SMAD protein phosphorylationIDAbiological_process
GO:2000138Positive regulation of cell proliferation involved in heart morphogenesisISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07691098360.96946591310.58601993631.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1959321426
GSE13712_SHEARUp0.2449131360
GSE13712_STATICUp0.1174805333
GSE19018Up0.1895279620
GSE19899_A1Up0.0760253423
GSE19899_A2Up0.2003832347
PubMed_21979375_A1Up0.2667053383
PubMed_21979375_A2Up0.0209572430
GSE35957Up0.0533332512
GSE36640Up0.0002592385
GSE54402Up0.1031035311
GSE9593Up0.1183253726
GSE43922Up0.0509677204
GSE24585Up0.0813920109
GSE37065Down-0.0444279634
GSE28863_A1Up0.0656419197
GSE28863_A2Up0.2885733563
GSE28863_A3Up0.2451696472
GSE28863_A4Up0.5335438320
GSE48662Up0.9136957430

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.