HCSGD entry for GLRB

1. General information

Official gene symbolGLRB
Entrez ID2743
Gene full nameglycine receptor, beta
Other gene symbolsHKPX2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001964Startle responseIMPbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0006811Ion transportIDAbiological_process
GO:0007218Neuropeptide signaling pathwayIDAbiological_process
GO:0007268Synaptic transmissionIMPbiological_process
GO:0007340Acrosome reactionIEAbiological_process
GO:0007399Nervous system developmentIMPbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0007628Adult walking behaviorIEAbiological_process
GO:0016594Glycine bindingIMPmolecular_function
GO:0016933Extracellular-glycine-gated ion channel activityIMPmolecular_function
GO:0016934Extracellular-glycine-gated chloride channel activityIDA TASmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0042391Regulation of membrane potentialIEAbiological_process
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0051291Protein heterooligomerizationIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0060012Synaptic transmission, glycinergicIEAbiological_process
GO:0060013Righting reflexIEAbiological_process
GO:1902476Chloride transmembrane transportIDA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00275424190.95712344900.14131461991.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0186074599
GSE13712_SHEARDown-0.1988930018
GSE13712_STATICUp0.0094125813
GSE19018Up0.1444983037
GSE19899_A1Up0.6247712244
GSE19899_A2Up0.8778153655
PubMed_21979375_A1Up0.6679170751
PubMed_21979375_A2Up0.9883750663
GSE35957Up0.1312217196
GSE36640Up1.7210304479
GSE54402Down-0.4873042721
GSE9593Up0.6203221752
GSE43922Up1.0290076844
GSE24585Up0.8363609258
GSE37065Up0.0248307621
GSE28863_A1Up0.3590436625
GSE28863_A2Up1.3880101468
GSE28863_A3Up0.0001797249
GSE28863_A4Down-0.1666690565
GSE48662Up0.0280379779

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GlycineDB00145 NUTR00028
EnfluraneDB00228 APRD00234

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.