HCSGD entry for GNB3
1. General information
| Official gene symbol | GNB3 |
|---|---|
| Entrez ID | 2784 |
| Gene full name | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | TAS | molecular_function |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006184 | GTP catabolic process | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008217 | Regulation of blood pressure | TAS | biological_process |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0044297 | Cell body | IEA | cellular_component |
| GO:0051020 | GTPase binding | IPI | molecular_function |
| GO:0071377 | Cellular response to glucagon stimulus | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9157238745 | 0.0891342844 | 0.9999902473 | 0.5665294544 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0178747083 |
| GSE13712_SHEAR | Up | 0.0745605016 |
| GSE13712_STATIC | Up | 0.2134275512 |
| GSE19018 | Down | -0.1863608533 |
| GSE19899_A1 | Down | -0.2349968645 |
| GSE19899_A2 | Down | -0.1190358709 |
| PubMed_21979375_A1 | Down | -0.3423159510 |
| PubMed_21979375_A2 | Up | 0.0218167128 |
| GSE35957 | Up | 0.0915919402 |
| GSE36640 | Up | 0.0023168481 |
| GSE54402 | Down | -0.0097645820 |
| GSE9593 | Down | -0.0082211986 |
| GSE43922 | Down | -0.1370058638 |
| GSE24585 | Down | -1.1662300695 |
| GSE37065 | Down | -0.0931109288 |
| GSE28863_A1 | Down | -0.0410462008 |
| GSE28863_A2 | Down | -0.0371902295 |
| GSE28863_A3 | Up | 0.1227158377 |
| GSE28863_A4 | Up | 0.1071560476 |
| GSE48662 | Down | -0.2935357348 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029954 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
