HCSGD entry for GPLD1

1. General information

Official gene symbolGPLD1
Entrez ID2822
Gene full nameglycosylphosphatidylinositol specific phospholipase D1
Other gene symbolsGPIPLD GPIPLDM PIGPLD PIGPLD1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001503OssificationISSbiological_process
GO:0002042Cell migration involved in sprouting angiogenesisIMPbiological_process
GO:0002062Chondrocyte differentiationISSbiological_process
GO:0002430Complement receptor mediated signaling pathwayIDAbiological_process
GO:0004621Glycosylphosphatidylinositol phospholipase D activityIDA TASmolecular_function
GO:0004630Phospholipase D activityIDAmolecular_function
GO:0005578Proteinaceous extracellular matrixISScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005622IntracellularIDAcellular_component
GO:0005737CytoplasmIDA ISScellular_component
GO:0005765Lysosomal membraneIDAcellular_component
GO:0006507GPI anchor releaseIDA IMPbiological_process
GO:0008285Negative regulation of cell proliferationIDAbiological_process
GO:0008286Insulin receptor signaling pathwayIDAbiological_process
GO:0009749Response to glucoseIDAbiological_process
GO:0010595Positive regulation of endothelial cell migrationIMPbiological_process
GO:0010694Positive regulation of alkaline phosphatase activityISSbiological_process
GO:0010867Positive regulation of triglyceride biosynthetic processISSbiological_process
GO:0010897Negative regulation of triglyceride catabolic processISSbiological_process
GO:0010907Positive regulation of glucose metabolic processISSbiological_process
GO:0010983Positive regulation of high-density lipoprotein particle clearanceISSbiological_process
GO:0017080Sodium channel regulator activityISSmolecular_function
GO:0032869Cellular response to insulin stimulusIDAbiological_process
GO:0035690Cellular response to drugIDAbiological_process
GO:0035701Hematopoietic stem cell migrationTASbiological_process
GO:0035774Positive regulation of insulin secretion involved in cellular response to glucose stimulusISSbiological_process
GO:0043065Positive regulation of apoptotic processIDAbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0045919Positive regulation of cytolysisIDAbiological_process
GO:0046470Phosphatidylcholine metabolic processISS TASbiological_process
GO:0051044Positive regulation of membrane protein ectodomain proteolysisIDAbiological_process
GO:0051047Positive regulation of secretionISSbiological_process
GO:0070633Transepithelial transportISSbiological_process
GO:0071277Cellular response to calcium ionIDAbiological_process
GO:0071397Cellular response to cholesterolIMPbiological_process
GO:0071401Cellular response to triglycerideIMPbiological_process
GO:0071467Cellular response to pHIDAbiological_process
GO:0097241Hematopoietic stem cell migration to bone marrowTASbiological_process
GO:1900076Regulation of cellular response to insulin stimulusIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.65199948330.91549207860.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0262050280
GSE13712_SHEARUp0.0063528809
GSE13712_STATICDown-0.0590594881
GSE19018Up0.0719668291
GSE19899_A1Up0.0516218065
GSE19899_A2Up0.1673492717
PubMed_21979375_A1Up0.1718582734
PubMed_21979375_A2Down-0.0400266030
GSE35957Up0.1233970295
GSE36640Up0.1270741175
GSE54402Down-0.0285146673
GSE9593Down-0.0304306245
GSE43922Up0.0124587894
GSE24585Up0.1496842227
GSE37065Up0.0268716363
GSE28863_A1Down-0.0094902945
GSE28863_A2Up0.0177877749
GSE28863_A3Up0.1616528335
GSE28863_A4Up0.1351532337
GSE48662Down-0.0493447604

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-505-3pMIMAT0002876MIRT040991CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.