HCSGD entry for LAMA1

1. General information

Official gene symbolLAMA1
Entrez ID284217
Gene full namelaminin, alpha 1
Other gene symbolsLAMA S-LAM-alpha
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002011Morphogenesis of an epithelial sheetIEAbiological_process
GO:0005102Receptor bindingIEAmolecular_function
GO:0005201Extracellular matrix structural constituentISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005578Proteinaceous extracellular matrixISScellular_component
GO:0005604Basement membraneIDAcellular_component
GO:0005606Laminin-1 complexIDA IPIcellular_component
GO:0005608Laminin-3 complexIPIcellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005911Cell-cell junctionIEAcellular_component
GO:0007155Cell adhesionIEAbiological_process
GO:0007166Cell surface receptor signaling pathwayISSbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0030155Regulation of cell adhesionIEAbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0030334Regulation of cell migrationIEAbiological_process
GO:0031012Extracellular matrixTAScellular_component
GO:0043208Glycosphingolipid bindingIEAmolecular_function
GO:0045198Establishment of epithelial cell apical/basal polarityIEAbiological_process
GO:0045995Regulation of embryonic developmentIEAbiological_process
GO:0060441Epithelial tube branching involved in lung morphogenesisIEAbiological_process
GO:0060445Branching involved in salivary gland morphogenesisIEAbiological_process
GO:0061304Retinal blood vessel morphogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67317105730.04412629460.99999024730.3949473308

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0288297416
GSE13712_SHEARDown-0.1251793100
GSE13712_STATICUp0.0678998927
GSE19018Up0.3998648503
GSE19899_A1Down-0.6902847950
GSE19899_A2Down-0.7912957208
PubMed_21979375_A1Down-0.7009088668
PubMed_21979375_A2Up0.0833279612
GSE35957Down-0.2714156795
GSE36640Down-0.7566378357
GSE54402Down-0.6990060502
GSE9593Up0.1159364427
GSE43922Down-0.8425234078
GSE24585Down-0.3942463394
GSE37065Up0.1261593819
GSE28863_A1Up0.3257915059
GSE28863_A2Up0.5748019851
GSE28863_A3Up0.0108710659
GSE28863_A4Up0.0551908937
GSE48662Up0.1044600727

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022954MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.