HCSGD entry for GRID2

1. General information

Official gene symbolGRID2
Entrez ID2895
Gene full nameglutamate receptor, ionotropic, delta 2
Other gene symbolsGluD2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004970Ionotropic glutamate receptor activityIEAmolecular_function
GO:0005234Extracellular-glutamate-gated ion channel activityIEAmolecular_function
GO:0005886Plasma membraneISScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0007157Heterophilic cell-cell adhesionISSbiological_process
GO:0007215Glutamate receptor signaling pathwayTASbiological_process
GO:0008066Glutamate receptor activityTASmolecular_function
GO:0008328Ionotropic glutamate receptor complexIEA ISScellular_component
GO:0010975Regulation of neuron projection developmentIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0021707Cerebellar granule cell differentiationISSbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0030165PDZ domain bindingIEA ISSmolecular_function
GO:0034613Cellular protein localizationIEA ISSbiological_process
GO:0035249Synaptic transmission, glutamatergicIEA ISSbiological_process
GO:0043197Dendritic spineIEA ISScellular_component
GO:0043523Regulation of neuron apoptotic processIEA ISSbiological_process
GO:0045202SynapseISScellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0060079Regulation of excitatory postsynaptic membrane potentialIEA ISSbiological_process
GO:0060134Prepulse inhibitionIEA ISSbiological_process
GO:0097110Scaffold protein bindingIEA ISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.19643085370.96858121270.85774314861.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0104403457
GSE13712_SHEARUp0.0287154109
GSE13712_STATICDown-0.0553786482
GSE19018Up0.0437673694
GSE19899_A1Up0.0489590023
GSE19899_A2Up0.4279490992
PubMed_21979375_A1Up0.2418968662
PubMed_21979375_A2Up0.0117272022
GSE35957Down-0.1369500230
GSE36640Up0.1140368967
GSE54402Down-0.1472820526
GSE9593Up0.0979915860
GSE43922Up0.0949968450
GSE24585Up0.8143235594
GSE37065Up0.0424520977
GSE28863_A1Up0.0595571002
GSE28863_A2Up0.0738193613
GSE28863_A3Up0.1313364338
GSE28863_A4Up0.0384300190
GSE48662Up0.2698579103

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.