HCSGD entry for GTF2H2

1. General information

Official gene symbolGTF2H2
Entrez ID2966
Gene full namegeneral transcription factor IIH, polypeptide 2, 44kDa
Other gene symbolsBTF2 BTF2P44 T-BTF2P44 TFIIH p44
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000439Core TFIIH complexIEAcellular_component
GO:0000718Nucleotide-excision repair, DNA damage removalTASbiological_process
GO:0002031G-protein coupled receptor internalizationIMPbiological_process
GO:0003676Nucleic acid bindingTASmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0004672Protein kinase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005675Holo TFIIH complexIDAcellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairIEA TASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006360Transcription from RNA polymerase I promoterTASbiological_process
GO:0006361Transcription initiation from RNA polymerase I promoterTASbiological_process
GO:0006362Transcription elongation from RNA polymerase I promoterTASbiological_process
GO:0006363Termination of RNA polymerase I transcriptionTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDA TASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0006412TranslationTASbiological_process
GO:0006468Protein phosphorylationIDAbiological_process
GO:0008094DNA-dependent ATPase activityIDAmolecular_function
GO:0008135Translation factor activity, nucleic acid bindingTASmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008353RNA polymerase II carboxy-terminal domain kinase activityIDAmolecular_function
GO:0009411Response to UVTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016310PhosphorylationIDAbiological_process
GO:0047485Protein N-terminus bindingIPImolecular_function
GO:0050434Positive regulation of viral transcriptionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99961886330.00030046350.99999024730.0316432000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-1.2526563265
GSE28863_A2Down-0.6706076604
GSE28863_A3Down-0.9467943708
GSE28863_A4Down-1.8207239850
GSE48662--

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-122-5pMIMAT0000421MIRT023302MicroarrayFunctional MTI (Weak)17612493
hsa-miR-30a-5pMIMAT0000087MIRT028505ProteomicsFunctional MTI (Weak)18668040
hsa-miR-324-3pMIMAT0000762MIRT042884CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.