HCSGD entry for GUCY1A2
1. General information
| Official gene symbol | GUCY1A2 |
|---|---|
| Entrez ID | 2977 |
| Gene full name | guanylate cyclase 1, soluble, alpha 2 |
| Other gene symbols | GC-SA2 GUC1A2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0004383 | Guanylate cyclase activity | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0030828 | Positive regulation of cGMP biosynthetic process | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4604294176 | 0.8959101022 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1084127057 |
| GSE13712_SHEAR | Down | -0.1813574656 |
| GSE13712_STATIC | Down | -0.2287231090 |
| GSE19018 | Up | 0.0387407188 |
| GSE19899_A1 | Up | 0.0525898224 |
| GSE19899_A2 | Up | 0.0646560253 |
| PubMed_21979375_A1 | Up | 0.3062428539 |
| PubMed_21979375_A2 | Up | 0.2086447236 |
| GSE35957 | Up | 0.0324713849 |
| GSE36640 | Up | 0.0735855397 |
| GSE54402 | Up | 0.1591268468 |
| GSE9593 | Up | 0.1735603971 |
| GSE43922 | Up | 0.1483782142 |
| GSE24585 | Down | -0.2664871364 |
| GSE37065 | Up | 0.1446182717 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0545372315 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Riociguat | DB08931 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017344 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
