HCSGD entry for GUCY2D


1. General information

Official gene symbolGUCY2D
Entrez ID3000
Gene full nameguanylate cyclase 2D, membrane (retina-specific)
Other gene symbolsCORD5 CORD6 CYGD GUC1A4 GUC2D LCA LCA1 RCD2 RETGC-1 ROS-GC1 ROSGC retGC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004383Guanylate cyclase activityIEAmolecular_function
GO:0004672Protein kinase activityIEAmolecular_function
GO:0004872Receptor activityTASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005640Nuclear outer membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007168Receptor guanylyl cyclase signaling pathwayTASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0016056Rhodopsin mediated signaling pathwayTASbiological_process
GO:0022400Regulation of rhodopsin mediated signaling pathwayTASbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0097381Photoreceptor disc membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75158153570.62163252920.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0565746474
GSE13712_SHEARDown-0.1749822360
GSE13712_STATICDown-0.1429398166
GSE19018Up0.0724932517
GSE19899_A1Up0.0036987391
GSE19899_A2Down-0.0897728905
PubMed_21979375_A1Down-0.1642766485
PubMed_21979375_A2Down-0.3272829053
GSE35957Up0.2963316668
GSE36640Up0.2394926595
GSE54402Up0.0418680002
GSE9593Down-0.0861103698
GSE43922Up0.1307424742
GSE24585Up0.0244526588
GSE37065Down-0.1178867246
GSE28863_A1Down-0.2048378359
GSE28863_A2Down-0.0392991359
GSE28863_A3Up0.3192857334
GSE28863_A4Up0.1692013401
GSE48662Down-0.0102519874

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.