HCSGD entry for GZMK

1. General information

Official gene symbolGZMK
Entrez ID3003
Gene full namegranzyme K (granzyme 3; tryptase II)
Other gene symbolsTRYP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004252Serine-type endopeptidase activityIEAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0008236Serine-type peptidase activityTASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.29410356750.91790122340.99410556051.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1018439473
GSE13712_SHEARUp0.0211322706
GSE13712_STATICUp0.1742653291
GSE19018Up0.3314393266
GSE19899_A1Up0.0034046056
GSE19899_A2Down-0.0828321077
PubMed_21979375_A1Down-0.1070259192
PubMed_21979375_A2Up0.0082189764
GSE35957Up0.2059929594
GSE36640Up0.1639756647
GSE54402Up0.1039601791
GSE9593Down-0.1063425097
GSE43922Up0.0165790988
GSE24585Up0.1331822973
GSE37065Down-0.0399503605
GSE28863_A1Up0.0682617554
GSE28863_A2Up0.2322154239
GSE28863_A3Up0.2747554584
GSE28863_A4Down-0.0041148574
GSE48662Up0.0398313601

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018327MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.