HCSGD entry for EHD2
1. General information
| Official gene symbol | EHD2 |
|---|---|
| Entrez ID | 30846 |
| Gene full name | EH-domain containing 2 |
| Other gene symbols | PAST2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | TAS | molecular_function |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA ISS | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0010008 | Endosome membrane | TAS | cellular_component |
| GO:0019904 | Protein domain specific binding | IEA | molecular_function |
| GO:0030866 | Cortical actin cytoskeleton organization | IEA | biological_process |
| GO:0032456 | Endocytic recycling | IGI | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0055038 | Recycling endosome membrane | IDA | cellular_component |
| GO:0072659 | Protein localization to plasma membrane | IEA ISS | biological_process |
| GO:1901741 | Positive regulation of myoblast fusion | IEA ISS | biological_process |
| GO:2001137 | Positive regulation of endocytic recycling | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9222239771 | 0.0061988260 | 0.9999902473 | 0.1605106195 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9814131324 |
| GSE13712_SHEAR | Up | 0.1125120558 |
| GSE13712_STATIC | Up | 0.1162818801 |
| GSE19018 | Down | -0.3028261759 |
| GSE19899_A1 | Down | -1.5011968890 |
| GSE19899_A2 | Down | -1.1825982683 |
| PubMed_21979375_A1 | Down | -1.0488512380 |
| PubMed_21979375_A2 | Down | -0.9347950412 |
| GSE35957 | Up | 0.0617184288 |
| GSE36640 | Down | -0.0311321909 |
| GSE54402 | Down | -1.0132606488 |
| GSE9593 | Up | 0.0962145830 |
| GSE43922 | Down | -0.7507130876 |
| GSE24585 | Down | -0.0606053274 |
| GSE37065 | Down | -0.5204730248 |
| GSE28863_A1 | Up | 0.2136402969 |
| GSE28863_A2 | Up | 0.2381385394 |
| GSE28863_A3 | Down | -0.0711683663 |
| GSE28863_A4 | Up | 0.1085157869 |
| GSE48662 | Up | 0.1477726034 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT004199 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022318 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
