HCSGD entry for FOXA3

1. General information

Official gene symbolFOXA3
Entrez ID3171
Gene full nameforkhead box A3
Other gene symbolsFKHH3 HNF3G TCF3G
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIBAbiological_process
GO:0001678Cellular glucose homeostasisIEA TASbiological_process
GO:0003690Double-stranded DNA bindingIBAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIDA IEA TASmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityIBAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexIBAcellular_component
GO:0006366Transcription from RNA polymerase II promoterIBAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0007389Pattern specification processIBAbiological_process
GO:0008134Transcription factor bindingIBA IEAmolecular_function
GO:0008301DNA binding, bendingIBAmolecular_function
GO:0009267Cellular response to starvationIEAbiological_process
GO:0009790Embryo developmentIBAbiological_process
GO:0009888Tissue developmentIBAbiological_process
GO:0010817Regulation of hormone levelsIBAbiological_process
GO:0016568Chromatin modificationIEAbiological_process
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0031018Endocrine pancreas developmentTASbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0044212Transcription regulatory region DNA bindingIMPmolecular_function
GO:0045666Positive regulation of neuron differentiationIBAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDA IEAbiological_process
GO:0048665Neuron fate specificationIBAbiological_process
GO:0051090Regulation of sequence-specific DNA binding transcription factor activityIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62255327690.70812475590.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0030639842
GSE13712_SHEARDown-0.1058888692
GSE13712_STATICDown-0.3043323934
GSE19018Up0.1561788090
GSE19899_A1Up0.0314225154
GSE19899_A2Up0.0558515548
PubMed_21979375_A1Down-0.1649738085
PubMed_21979375_A2Down-0.0543526927
GSE35957Down-0.0443186667
GSE36640Up0.1115833062
GSE54402Up0.0217447027
GSE9593Down-0.0277343329
GSE43922Up0.0870406880
GSE24585Up0.1344956389
GSE37065Down-0.0338364932
GSE28863_A1Up0.0049454882
GSE28863_A2Down-0.1369937556
GSE28863_A3Up0.4477835216
GSE28863_A4Down-0.0780345966
GSE48662Up0.1020271043

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017722MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.