HCSGD entry for KCNJ3


1. General information

Official gene symbolKCNJ3
Entrez ID3760
Gene full namepotassium inwardly-rectifying channel, subfamily J, member 3
Other gene symbolsGIRK1 KGA KIR3.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005242Inward rectifier potassium channel activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexTAScellular_component
GO:0009897External side of plasma membraneIEAcellular_component
GO:0015467G-protein activated inward rectifier potassium channel activityIEAmolecular_function
GO:0030315T-tubuleIEAcellular_component
GO:0034220Ion transmembrane transportIDA TASbiological_process
GO:0051602Response to electrical stimulusIEAbiological_process
GO:0055085Transmembrane transportIDA TASbiological_process
GO:0071805Potassium ion transmembrane transportIDA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.58747930550.88970964630.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0254458795
GSE13712_SHEARDown-0.0207183043
GSE13712_STATICDown-0.0435552287
GSE19018Down-0.0543692049
GSE19899_A1Up0.0692432797
GSE19899_A2Up0.0535622649
PubMed_21979375_A1Up0.2548210405
PubMed_21979375_A2Down-0.1803556027
GSE35957Up0.1507454518
GSE36640Up0.0350952515
GSE54402Up0.0000189103
GSE9593Down-0.0986303410
GSE43922Up0.0560309114
GSE24585Up0.3878066496
GSE37065Down-0.1279530368
GSE28863_A1Down-0.0731652425
GSE28863_A2Up0.3158576730
GSE28863_A3Up0.1015959733
GSE28863_A4Up0.0956040720
GSE48662Up0.0496179706

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.