HCSGD entry for HELT

1. General information

Official gene symbolHELT
Entrez ID391723
Gene full namehelt bHLH transcription factor
Other gene symbolsHCM1228 HESL Mgn bHLHb44
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0001967Suckling behaviorIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0007417Central nervous system developmentIEAbiological_process
GO:0009791Post-embryonic developmentIEAbiological_process
GO:0010259Multicellular organismal agingIEAbiological_process
GO:0021858GABAergic neuron differentiation in basal gangliaIEAbiological_process
GO:0035264Multicellular organism growthIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0046983Protein dimerization activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56080544810.96013823940.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.1542991984
GSE24585Down-0.1274933045
GSE37065Up0.0773845901
GSE28863_A1Down-0.1442988961
GSE28863_A2Up0.1457835545
GSE28863_A3Up0.1699121255
GSE28863_A4Up0.1103002922
GSE48662Up0.0337126436

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.