HCSGD entry for LIPC
1. General information
| Official gene symbol | LIPC |
|---|---|
| Entrez ID | 3990 |
| Gene full name | lipase, hepatic |
| Other gene symbols | HDLCQ12 HL HTGL LIPH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004620 | Phospholipase activity | TAS | molecular_function |
| GO:0004806 | Triglyceride lipase activity | IDA IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0006629 | Lipid metabolic process | IEA | biological_process |
| GO:0006633 | Fatty acid biosynthetic process | IDA | biological_process |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0008203 | Cholesterol metabolic process | IEA | biological_process |
| GO:0019433 | Triglyceride catabolic process | IDA | biological_process |
| GO:0030169 | Low-density lipoprotein particle binding | ISS | molecular_function |
| GO:0034185 | Apolipoprotein binding | ISS | molecular_function |
| GO:0034364 | High-density lipoprotein particle | IEA | cellular_component |
| GO:0034372 | Very-low-density lipoprotein particle remodeling | IDA | biological_process |
| GO:0034373 | Intermediate-density lipoprotein particle remodeling | TAS | biological_process |
| GO:0034374 | Low-density lipoprotein particle remodeling | IMP | biological_process |
| GO:0034375 | High-density lipoprotein particle remodeling | IMP | biological_process |
| GO:0034382 | Chylomicron remnant clearance | TAS | biological_process |
| GO:0034638 | Phosphatidylcholine catabolic process | TAS | biological_process |
| GO:0042632 | Cholesterol homeostasis | IMP | biological_process |
| GO:0043691 | Reverse cholesterol transport | IC | biological_process |
| GO:0070328 | Triglyceride homeostasis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4142044109 | 0.4735005205 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0849162607 |
| GSE13712_SHEAR | Down | -0.0815153500 |
| GSE13712_STATIC | Up | 0.0247239293 |
| GSE19018 | Down | -0.1875464574 |
| GSE19899_A1 | Down | -0.0398421587 |
| GSE19899_A2 | Down | -0.0074599811 |
| PubMed_21979375_A1 | Down | -0.1727802403 |
| PubMed_21979375_A2 | Down | -0.3530313684 |
| GSE35957 | Down | -0.5423522388 |
| GSE36640 | Up | 0.0270899263 |
| GSE54402 | Down | -0.0435522131 |
| GSE9593 | Up | 0.0361838380 |
| GSE43922 | Up | 0.0139535197 |
| GSE24585 | Up | 0.0236950594 |
| GSE37065 | Up | 0.2556350904 |
| GSE28863_A1 | Up | 0.4127787948 |
| GSE28863_A2 | Up | 0.6104631070 |
| GSE28863_A3 | Up | 0.2190665503 |
| GSE28863_A4 | Up | 0.0052426420 |
| GSE48662 | Up | 0.1936270562 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019266 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-1 | MIMAT0000416 | MIRT023497 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
