HCSGD entry for LMX1B

1. General information

Official gene symbolLMX1B
Entrez ID4010
Gene full nameLIM homeobox transcription factor 1, beta
Other gene symbolsLMX1.2 NPS1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001701In utero embryonic developmentNASbiological_process
GO:0001764Neuron migrationIEAbiological_process
GO:0002930Trabecular meshwork developmentIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIDAbiological_process
GO:0007275Multicellular organismal developmentNASbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008283Cell proliferationIEAbiological_process
GO:0009953Dorsal/ventral pattern formationIEA ISSbiological_process
GO:0021587Cerebellum morphogenesisIEAbiological_process
GO:0021954Central nervous system neuron developmentIEAbiological_process
GO:0030182Neuron differentiationISSbiological_process
GO:0030199Collagen fibril organizationIEAbiological_process
GO:0030901Midbrain developmentIEAbiological_process
GO:0035108Limb morphogenesisIEAbiological_process
GO:0035265Organ growthIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0071542Dopaminergic neuron differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.29176204170.84182473690.99111840241.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0842044222
GSE13712_SHEARUp0.0553298431
GSE13712_STATICDown-0.1042070198
GSE19018Up0.1146513558
GSE19899_A1Up0.0179795855
GSE19899_A2Up0.0722141203
PubMed_21979375_A1Up0.0542995883
PubMed_21979375_A2Down-0.1300268276
GSE35957Down-0.0561295535
GSE36640Up0.1707374623
GSE54402Up0.0250903381
GSE9593Down-0.0487166093
GSE43922Up0.2063063159
GSE24585Down-0.0099503068
GSE37065Down-0.1467552390
GSE28863_A1Down-0.0840506665
GSE28863_A2Down-0.1976123403
GSE28863_A3Up0.5787615272
GSE28863_A4Up0.3833440626
GSE48662Up0.0585326653

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.