HCSGD entry for MAN2A2
1. General information
| Official gene symbol | MAN2A2 |
|---|---|
| Entrez ID | 4122 |
| Gene full name | mannosidase, alpha, class 2A, member 2 |
| Other gene symbols | MANA2X |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0004559 | Alpha-mannosidase activity | IEA | molecular_function |
| GO:0004572 | Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity | IEA | molecular_function |
| GO:0005975 | Carbohydrate metabolic process | IEA | biological_process |
| GO:0006013 | Mannose metabolic process | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0015923 | Mannosidase activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016799 | Hydrolase activity, hydrolyzing N-glycosyl compounds | IEA | molecular_function |
| GO:0018279 | Protein N-linked glycosylation via asparagine | TAS | biological_process |
| GO:0030246 | Carbohydrate binding | IEA | molecular_function |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0906134797 | 0.4772951332 | 0.6329717091 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0566222994 |
| GSE13712_SHEAR | Down | -0.5342571632 |
| GSE13712_STATIC | Down | -0.4014150439 |
| GSE19018 | Up | 0.3021025788 |
| GSE19899_A1 | Down | -0.0370155688 |
| GSE19899_A2 | Down | -0.0548122527 |
| PubMed_21979375_A1 | Down | -0.6923145840 |
| PubMed_21979375_A2 | Up | 0.0112365070 |
| GSE35957 | Down | -0.0487954793 |
| GSE36640 | Up | 1.5569987276 |
| GSE54402 | Down | -0.2640138327 |
| GSE9593 | Up | 0.2118795728 |
| GSE43922 | Up | 0.3366738401 |
| GSE24585 | Down | -0.3281784196 |
| GSE37065 | Up | 0.0870702428 |
| GSE28863_A1 | Up | 0.8372813025 |
| GSE28863_A2 | Up | 0.7362591895 |
| GSE28863_A3 | Up | 0.0877680372 |
| GSE28863_A4 | Down | -0.0881664529 |
| GSE48662 | Up | 0.3650871078 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024425 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026963 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-484 | MIMAT0002174 | MIRT042114 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
