HCSGD entry for MATK
1. General information
| Official gene symbol | MATK |
|---|---|
| Entrez ID | 4145 |
| Gene full name | megakaryocyte-associated tyrosine kinase |
| Other gene symbols | CHK CTK HHYLTK HYL HYLTK Lsk |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004713 | Protein tyrosine kinase activity | IEA TAS | molecular_function |
| GO:0004715 | Non-membrane spanning protein tyrosine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
| GO:0007498 | Mesoderm development | TAS | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0018108 | Peptidyl-tyrosine phosphorylation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5998807188 | 0.4757037271 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0667634277 |
| GSE13712_SHEAR | Down | -0.1488288982 |
| GSE13712_STATIC | Up | 0.0038301690 |
| GSE19018 | Down | -0.0584973728 |
| GSE19899_A1 | Down | -0.2122706559 |
| GSE19899_A2 | Up | 0.2513340369 |
| PubMed_21979375_A1 | Up | 0.1866702002 |
| PubMed_21979375_A2 | Down | -0.0433435367 |
| GSE35957 | Up | 0.1369061476 |
| GSE36640 | Up | 0.0734255433 |
| GSE54402 | Up | 0.0357879836 |
| GSE9593 | Up | 0.2048487142 |
| GSE43922 | Up | 0.0913680736 |
| GSE24585 | Down | -0.4046105458 |
| GSE37065 | Down | -0.1481739762 |
| GSE28863_A1 | Up | 0.1618221139 |
| GSE28863_A2 | Down | -0.4110805871 |
| GSE28863_A3 | Up | 0.3463557723 |
| GSE28863_A4 | Up | 0.0148796153 |
| GSE48662 | Up | 0.0092219185 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017676 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
