HCSGD entry for MYH11

1. General information

Official gene symbolMYH11
Entrez ID4629
Gene full namemyosin, heavy chain 11, smooth muscle
Other gene symbolsAAT4 FAA4 SMHC SMMHC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001725Stress fiberIEAcellular_component
GO:0003774Motor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005859Muscle myosin complexIEAcellular_component
GO:0006936Muscle contractionTASbiological_process
GO:0006939Smooth muscle contractionISSbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008307Structural constituent of muscleIMPmolecular_function
GO:0030241Skeletal muscle myosin thick filament assemblyISSbiological_process
GO:0030485Smooth muscle contractile fiberIEAcellular_component
GO:0032982Myosin filamentIEAcellular_component
GO:0042470MelanosomeIEAcellular_component
GO:0048251Elastic fiber assemblyIMPbiological_process
GO:0048739Cardiac muscle fiber developmentIMPbiological_process
GO:0051015Actin filament bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80981268570.63320598000.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0349873091
GSE13712_SHEARDown-0.0139374921
GSE13712_STATICUp0.0303310659
GSE19018Down-0.3436537371
GSE19899_A1Up0.0768203652
GSE19899_A2Down-0.0169291227
PubMed_21979375_A1Down-0.0978077338
PubMed_21979375_A2Down-0.2043138130
GSE35957Down-0.0743611937
GSE36640Up0.2180821770
GSE54402Down-0.2201567337
GSE9593Down-0.0548901292
GSE43922Up0.0533792489
GSE24585Down-0.0486074359
GSE37065Down-0.0171815049
GSE28863_A1Down-0.0891433340
GSE28863_A2Down-0.0845831110
GSE28863_A3Up0.2054944652
GSE28863_A4Up0.1714882778
GSE48662Up0.2762091986

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Tetrafluoroaluminate IonDB04444 EXPT00497

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.