HCSGD entry for NFKBIL1


1. General information

Official gene symbolNFKBIL1
Entrez ID4795
Gene full namenuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
Other gene symbolsIKBL LST1 NFKBIL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0007249I-kappaB kinase/NF-kappaB signalingIEAbiological_process
GO:0031665Negative regulation of lipopolysaccharide-mediated signaling pathwayIDAbiological_process
GO:0032088Negative regulation of NF-kappaB transcription factor activityIDAbiological_process
GO:0032720Negative regulation of tumor necrosis factor productionIMPbiological_process
GO:0034122Negative regulation of toll-like receptor signaling pathwayIDAbiological_process
GO:0042994Cytoplasmic sequestering of transcription factorTASbiological_process
GO:0071222Cellular response to lipopolysaccharideIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.51080185400.34559161890.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1168311963
GSE13712_SHEARUp0.1312939865
GSE13712_STATICUp0.2502739440
GSE19018Up0.0890256380
GSE19899_A1Down-0.0564222364
GSE19899_A2Down-0.2128596451
PubMed_21979375_A1Down-0.0361058871
PubMed_21979375_A2Down-0.4667136761
GSE35957Down-0.4224058562
GSE36640Up0.0300260344
GSE54402Up0.0220246852
GSE9593Up0.3614033518
GSE43922Up0.0487888455
GSE24585Up0.2903912520
GSE37065Down-0.0176930857
GSE28863_A1Down-0.1201064878
GSE28863_A2Down-0.2066342995
GSE28863_A3Up0.1228408332
GSE28863_A4Down-0.5077084787
GSE48662Up0.4938751749

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-93-3pMIMAT0004509MIRT038896CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.