HCSGD entry for NPAS1
1. General information
| Official gene symbol | NPAS1 |
|---|---|
| Entrez ID | 4861 |
| Gene full name | neuronal PAS domain protein 1 |
| Other gene symbols | MOP5 PASD5 bHLHe11 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0001964 | Startle response | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007417 | Central nervous system development | TAS | biological_process |
| GO:0042711 | Maternal behavior | IEA | biological_process |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5556988260 | 0.1691487102 | 0.9999902473 | 0.7956634382 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1956510712 |
| GSE13712_SHEAR | Down | -0.2205744394 |
| GSE13712_STATIC | Down | -0.1112863371 |
| GSE19018 | Up | 0.0728784854 |
| GSE19899_A1 | Down | -0.1333303959 |
| GSE19899_A2 | Up | 0.3769288931 |
| PubMed_21979375_A1 | Up | 0.0069685276 |
| PubMed_21979375_A2 | Down | -0.0422456036 |
| GSE35957 | Down | -0.1134720224 |
| GSE36640 | Up | 0.2459788339 |
| GSE54402 | Down | -0.0076456789 |
| GSE9593 | Down | -0.1762473516 |
| GSE43922 | Up | 0.0455967818 |
| GSE24585 | Up | 0.5674165811 |
| GSE37065 | Down | -0.0646875702 |
| GSE28863_A1 | Down | -0.3503598435 |
| GSE28863_A2 | Down | -0.6931906964 |
| GSE28863_A3 | Down | -0.4201888663 |
| GSE28863_A4 | Down | -0.0645347888 |
| GSE48662 | Up | 1.2673938295 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017075 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
