HCSGD entry for NSF
1. General information
| Official gene symbol | NSF |
|---|---|
| Entrez ID | 4905 |
| Gene full name | N-ethylmaleimide-sensitive factor |
| Other gene symbols | SKD2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001921 | Positive regulation of receptor recycling | IDA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006813 | Potassium ion transport | IEA | biological_process |
| GO:0006887 | Exocytosis | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0019905 | Syntaxin binding | IEA | molecular_function |
| GO:0030165 | PDZ domain binding | IPI | molecular_function |
| GO:0032403 | Protein complex binding | IDA | molecular_function |
| GO:0042623 | ATPase activity, coupled | IEA | molecular_function |
| GO:0045026 | Plasma membrane fusion | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0500596102 | 0.9896035827 | 0.4896391676 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1590769201 |
| GSE13712_SHEAR | Down | -0.0382739406 |
| GSE13712_STATIC | Up | 0.0702981450 |
| GSE19018 | Up | 0.4696855595 |
| GSE19899_A1 | Up | 0.1412420651 |
| GSE19899_A2 | Up | 0.2293403484 |
| PubMed_21979375_A1 | Up | 0.2248480540 |
| PubMed_21979375_A2 | Up | 0.1534944804 |
| GSE35957 | Up | 0.5971089266 |
| GSE36640 | Up | 0.2127567652 |
| GSE54402 | Up | 0.0424321814 |
| GSE9593 | Down | -0.1110927426 |
| GSE43922 | Up | 0.0475424959 |
| GSE24585 | Up | 0.8638178410 |
| GSE37065 | Up | 0.0513870952 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0427389820 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 1-Ethyl-Pyrrolidine-2,5-Dione | DB01902 | EXPT02325 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024525 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026250 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT026983 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029069 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031568 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036828 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041241 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048424 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
