HCSGD entry for OXCT1

1. General information

Official gene symbolOXCT1
Entrez ID5019
Gene full name3-oxoacid CoA transferase 1
Other gene symbolsOXCT SCOT
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005739MitochondrionIDA IEA NAScellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0007420Brain developmentIEAbiological_process
GO:0007507Heart developmentIEAbiological_process
GO:0007584Response to nutrientIEAbiological_process
GO:00082603-oxoacid CoA-transferase activityIEA IMP TASmolecular_function
GO:0008410CoA-transferase activityIEAmolecular_function
GO:0009725Response to hormoneIEAbiological_process
GO:0014823Response to activityIEAbiological_process
GO:0032024Positive regulation of insulin secretionIEAbiological_process
GO:0042182Ketone catabolic processIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042594Response to starvationIEAbiological_process
GO:0042803Protein homodimerization activityIEA NASmolecular_function
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045471Response to ethanolIEAbiological_process
GO:0046950Cellular ketone body metabolic processIMP TASbiological_process
GO:0046952Ketone body catabolic processIEA TASbiological_process
GO:0060612Adipose tissue developmentIEAbiological_process
GO:0071229Cellular response to acidIEAbiological_process
GO:0071333Cellular response to glucose stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99619162270.00009932750.99999024730.0175463087

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5775868576
GSE13712_SHEARDown-1.3152035585
GSE13712_STATICDown-0.5822070720
GSE19018Down-1.5694690926
GSE19899_A1Down-2.0660255341
GSE19899_A2Down-3.0502207189
PubMed_21979375_A1Down-3.5585088397
PubMed_21979375_A2Down-4.3839092014
GSE35957Down-0.3140320317
GSE36640Down-0.4436507118
GSE54402Down-0.8846140441
GSE9593Up0.1235223802
GSE43922Down-2.1954137647
GSE24585Up0.1957609110
GSE37065Down-0.0172975380
GSE28863_A1Down-0.0779517295
GSE28863_A2Down-0.0048524086
GSE28863_A3Down-0.1935040936
GSE28863_A4Down-0.0201157409
GSE48662Down-0.5615843980

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Ethylmercurithiosalicylic acidDB02731 EXPT01342

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020769ProteomicsFunctional MTI (Weak)18668040
hsa-miR-1MIMAT0000416MIRT023755Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT029445MicroarrayFunctional MTI (Weak)19088304
hsa-miR-100-5pMIMAT0000098MIRT048474CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.