HCSGD entry for PAFAH1B2
1. General information
| Official gene symbol | PAFAH1B2 |
|---|---|
| Entrez ID | 5049 |
| Gene full name | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity | IEA | molecular_function |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA TAS | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006629 | Lipid metabolic process | TAS | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0007420 | Brain development | IEA | biological_process |
| GO:0016042 | Lipid catabolic process | IEA | biological_process |
| GO:0016239 | Positive regulation of macroautophagy | IMP | biological_process |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1529511911 | 0.8773914935 | 0.7798500872 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1747403576 |
| GSE13712_SHEAR | Up | 0.3339842741 |
| GSE13712_STATIC | Up | 0.0821053540 |
| GSE19018 | Up | 0.3756554345 |
| GSE19899_A1 | Up | 0.2626807219 |
| GSE19899_A2 | Up | 0.5466437397 |
| PubMed_21979375_A1 | Up | 0.1487518244 |
| PubMed_21979375_A2 | Up | 0.2685331536 |
| GSE35957 | Up | 0.1362959593 |
| GSE36640 | Down | -0.0382238756 |
| GSE54402 | Up | 0.2045846109 |
| GSE9593 | Down | -0.0453381543 |
| GSE43922 | Up | 0.1552787786 |
| GSE24585 | Down | -0.1166594702 |
| GSE37065 | Up | 0.0868899557 |
| GSE28863_A1 | Down | -0.3541674266 |
| GSE28863_A2 | Up | 0.1133249499 |
| GSE28863_A3 | Down | -0.7274055511 |
| GSE28863_A4 | Up | 0.0751160079 |
| GSE48662 | Down | -0.1693545106 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001434 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005183 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039716 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
