HCSGD entry for DUOX2


1. General information

Official gene symbolDUOX2
Entrez ID50506
Gene full namedual oxidase 2
Other gene symbolsLNOX2 NOXEF2 P138-TOX TDH6 THOX2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004601Peroxidase activityIEAmolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0006590Thyroid hormone generationIEAbiological_process
GO:0009615Response to virusIDAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016174NAD(P)H oxidase activityIDAmolecular_function
GO:0016324Apical plasma membraneIEAcellular_component
GO:0019221Cytokine-mediated signaling pathwayIDA ISSbiological_process
GO:0020037Heme bindingIEAmolecular_function
GO:0042335Cuticle developmentISSbiological_process
GO:0042446Hormone biosynthetic processIEAbiological_process
GO:0042744Hydrogen peroxide catabolic processIEAbiological_process
GO:0051591Response to cAMPIDA ISSbiological_process
GO:0055114Oxidation-reduction processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74541222980.67745374800.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0566667516
GSE13712_SHEARDown-0.0239900462
GSE13712_STATICDown-0.2284141719
GSE19018Up0.1536769504
GSE19899_A1Down-0.0124426493
GSE19899_A2Up0.3273259920
PubMed_21979375_A1Down-0.1316357887
PubMed_21979375_A2Up0.1119888817
GSE35957Up0.0112700768
GSE36640Up0.0637227787
GSE54402Down-0.0331228351
GSE9593Up0.0412194695
GSE43922Up0.0118401650
GSE24585Up0.0830282785
GSE37065Down-0.0210693154
GSE28863_A1Down-0.0854038640
GSE28863_A2Down-0.1559807800
GSE28863_A3Up0.2069297745
GSE28863_A4Down-0.0423015328
GSE48662Up0.1092951549

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.