HCSGD entry for COPS7A


1. General information

Official gene symbolCOPS7A
Entrez ID50813
Gene full nameCOP9 signalosome subunit 7A
Other gene symbolsCSN7A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDA IEAcellular_component
GO:0008180COP9 signalosomeIDA IEAcellular_component
GO:0010388Cullin deneddylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.20125239160.65992389730.86526693891.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3277219661
GSE13712_SHEARDown-0.0281561065
GSE13712_STATICUp0.0645261233
GSE19018Up0.5546083125
GSE19899_A1Down-0.3243040337
GSE19899_A2Down-0.0548776256
PubMed_21979375_A1Up0.6364096824
PubMed_21979375_A2Down-0.5534511541
GSE35957Up0.0448413931
GSE36640Up0.8216179291
GSE54402Up0.0441655277
GSE9593Up0.2341282030
GSE43922Down-0.1914959764
GSE24585Up0.0409534972
GSE37065Down-0.1838806561
GSE28863_A1Up0.0777962421
GSE28863_A2Up0.0804952681
GSE28863_A3Down-0.2896693964
GSE28863_A4Up0.1250139037
GSE48662Up0.2220445550

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024503MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026890MicroarrayFunctional MTI (Weak)19074876
hsa-miR-24-3pMIMAT0000080MIRT030594MicroarrayFunctional MTI (Weak)19748357
hsa-miR-423-5pMIMAT0004748MIRT038117CLASHFunctional MTI (Weak)23622248
hsa-miR-361-5pMIMAT0000703MIRT044110CLASHFunctional MTI (Weak)23622248
hsa-miR-30d-5pMIMAT0000245MIRT047795CLASHFunctional MTI (Weak)23622248
hsa-miR-107MIMAT0000104MIRT048306CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.