HCSGD entry for HSD17B12
1. General information
| Official gene symbol | HSD17B12 |
|---|---|
| Entrez ID | 51144 |
| Gene full name | hydroxysteroid (17-beta) dehydrogenase 12 |
| Other gene symbols | KAR SDR12C1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001968 | Fibronectin binding | IEA | molecular_function |
| GO:0004303 | Estradiol 17-beta-dehydrogenase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005518 | Collagen binding | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006633 | Fatty acid biosynthetic process | IEA | biological_process |
| GO:0006703 | Estrogen biosynthetic process | IEA | biological_process |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0010811 | Positive regulation of cell-substrate adhesion | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0019432 | Triglyceride biosynthetic process | TAS | biological_process |
| GO:0030198 | Extracellular matrix organization | IEA | biological_process |
| GO:0031012 | Extracellular matrix | IEA | cellular_component |
| GO:0035338 | Long-chain fatty-acyl-CoA biosynthetic process | TAS | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4160255233 | 0.8448593822 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2077044195 |
| GSE13712_SHEAR | Down | -0.0133355240 |
| GSE13712_STATIC | Up | 0.2688534385 |
| GSE19018 | Down | -0.1383981087 |
| GSE19899_A1 | Down | -0.0786911316 |
| GSE19899_A2 | Up | 0.2017792783 |
| PubMed_21979375_A1 | Down | -0.1405894102 |
| PubMed_21979375_A2 | Up | 0.3189030737 |
| GSE35957 | Up | 0.1975711325 |
| GSE36640 | Up | 0.5249898908 |
| GSE54402 | Down | -0.2976832457 |
| GSE9593 | Up | 0.0172776442 |
| GSE43922 | Down | -0.0765814658 |
| GSE24585 | Up | 0.0530871865 |
| GSE37065 | Up | 0.1469990682 |
| GSE28863_A1 | Up | 0.0807339984 |
| GSE28863_A2 | Down | -0.0029201700 |
| GSE28863_A3 | Down | -0.1886056598 |
| GSE28863_A4 | Up | 0.0574224435 |
| GSE48662 | Up | 0.0505865583 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001545 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-874-3p | MIMAT0004911 | MIRT037759 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-191-5p | MIMAT0000440 | MIRT045813 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
