HCSGD entry for PCNT

1. General information

Official gene symbolPCNT
Entrez ID5116
Gene full namepericentrin
Other gene symbolsKEN MOPD2 PCN PCNT2 PCNTB PCTN2 SCKL4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000226Microtubule cytoskeleton organizationIMPbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0001764Neuron migrationIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005814CentrioleIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005874MicrotubuleIEAcellular_component
GO:0007051Spindle organizationIEAbiological_process
GO:0021696Cerebellar cortex morphogenesisIEAbiological_process
GO:0021772Olfactory bulb developmentIEAbiological_process
GO:0035108Limb morphogenesisIEAbiological_process
GO:0035264Multicellular organism growthIEAbiological_process
GO:0042384Cilium assemblyIDAbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0045171Intercellular bridgeIEAcellular_component
GO:0048854Brain morphogenesisIEAbiological_process
GO:0061351Neural precursor cell proliferationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.85030710460.16327598880.99999024730.7809535344

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0512546881
GSE13712_SHEARUp0.0447832794
GSE13712_STATICDown-0.1388636606
GSE19018Down-0.0237852615
GSE19899_A1Down-0.0942419171
GSE19899_A2Down-1.3128792604
PubMed_21979375_A1Down-0.1929214155
PubMed_21979375_A2Down-0.3263289625
GSE35957Down-0.2341204056
GSE36640Down-1.2801245872
GSE54402Up0.0773838960
GSE9593Down-0.0344682891
GSE43922Down-0.0493496076
GSE24585Up0.0890976271
GSE37065Up0.0516693772
GSE28863_A1Up0.1112700384
GSE28863_A2Up0.1138708388
GSE28863_A3Up0.3226728207
GSE28863_A4Up0.1015798996
GSE48662Down-0.2159380016

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016284MicroarrayFunctional MTI (Weak)20304954
hsa-miR-155-5pMIMAT0000646MIRT020608ProteomicsFunctional MTI (Weak)18668040
hsa-miR-30a-5pMIMAT0000087MIRT028428ProteomicsFunctional MTI (Weak)18668040
hsa-miR-26b-5pMIMAT0000083MIRT029023MicroarrayFunctional MTI (Weak)19088304
hsa-miR-615-3pMIMAT0003283MIRT040017CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041629CLASHFunctional MTI (Weak)23622248
hsa-miR-30e-5pMIMAT0000692MIRT044148CLASHFunctional MTI (Weak)23622248
hsa-miR-30b-5pMIMAT0000420MIRT046166CLASHFunctional MTI (Weak)23622248
hsa-miR-222-3pMIMAT0000279MIRT046776CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.