HCSGD entry for WNT16
1. General information
| Official gene symbol | WNT16 |
|---|---|
| Entrez ID | 51384 |
| Gene full name | wingless-type MMTV integration site family, member 16 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003408 | Optic cup formation involved in camera-type eye development | ISS | biological_process |
| GO:0005102 | Receptor binding | IEA | molecular_function |
| GO:0005109 | Frizzled binding | IBA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0010628 | Positive regulation of gene expression | IMP | biological_process |
| GO:0014068 | Positive regulation of phosphatidylinositol 3-kinase signaling | IMP | biological_process |
| GO:0016055 | Wnt signaling pathway | IBA IEA | biological_process |
| GO:0030182 | Neuron differentiation | IBA | biological_process |
| GO:0030216 | Keratinocyte differentiation | IMP | biological_process |
| GO:0043616 | Keratinocyte proliferation | IMP | biological_process |
| GO:0045165 | Cell fate commitment | IBA | biological_process |
| GO:0046330 | Positive regulation of JNK cascade | IMP | biological_process |
| GO:0060317 | Cardiac epithelial to mesenchymal transition | IEA | biological_process |
| GO:0060548 | Negative regulation of cell death | IMP | biological_process |
| GO:0090399 | Replicative senescence | IMP | biological_process |
| GO:0090403 | Oxidative stress-induced premature senescence | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0758124653 | 0.2059390031 | 0.5826160292 | 0.8805263970 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0641564782 |
| GSE13712_SHEAR | Down | -0.0569595473 |
| GSE13712_STATIC | Down | -0.1121928637 |
| GSE19018 | Down | -0.1796599281 |
| GSE19899_A1 | Down | -0.0752372752 |
| GSE19899_A2 | Up | 0.1804000504 |
| PubMed_21979375_A1 | Down | -0.5357375204 |
| PubMed_21979375_A2 | Up | 0.2855332300 |
| GSE35957 | Up | 1.4479728372 |
| GSE36640 | Up | 4.1518973648 |
| GSE54402 | Down | -1.4669654867 |
| GSE9593 | Down | -0.0062900317 |
| GSE43922 | Down | -0.1343073133 |
| GSE24585 | Up | 0.0563689318 |
| GSE37065 | Up | 0.2971578154 |
| GSE28863_A1 | Down | -0.4776790192 |
| GSE28863_A2 | Up | 0.4346923723 |
| GSE28863_A3 | Up | 0.0315818052 |
| GSE28863_A4 | Up | 0.0531379090 |
| GSE48662 | Down | -0.1917003093 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025130 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
