HCSGD entry for DDX41
1. General information
| Official gene symbol | DDX41 |
|---|---|
| Entrez ID | 51428 |
| Gene full name | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 |
| Other gene symbols | ABS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | IC | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006396 | RNA processing | TAS | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0032479 | Regulation of type I interferon production | TAS | biological_process |
| GO:0032481 | Positive regulation of type I interferon production | TAS | biological_process |
| GO:0035458 | Cellular response to interferon-beta | IEA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3020201284 | 0.1017760191 | 0.9999004654 | 0.6109206385 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9769554482 |
| GSE13712_SHEAR | Down | -0.1291882851 |
| GSE13712_STATIC | Down | -0.1515262690 |
| GSE19018 | Up | 0.1368538974 |
| GSE19899_A1 | Down | -0.9272071106 |
| GSE19899_A2 | Up | 0.2545783314 |
| PubMed_21979375_A1 | Up | 0.3237020213 |
| PubMed_21979375_A2 | Up | 1.0540870445 |
| GSE35957 | Down | -0.3816042749 |
| GSE36640 | Down | -0.3309021060 |
| GSE54402 | Up | 0.4744615678 |
| GSE9593 | Up | 0.0227332287 |
| GSE43922 | Down | -0.0309821795 |
| GSE24585 | Down | -0.0115799865 |
| GSE37065 | Up | 0.0212292131 |
| GSE28863_A1 | Up | 0.0548297238 |
| GSE28863_A2 | Up | 0.3585418588 |
| GSE28863_A3 | Down | -0.0752636691 |
| GSE28863_A4 | Down | -0.3920500847 |
| GSE48662 | Up | 0.4409783532 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031540 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032281 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT041875 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 24677687 | Presented are applications of flow- and laser scanning- cytometry utilizing phospho-specific Abs, to monitor activation along these pathways in response to the reported antiaging drugs rapamycin, metformin, berberine, resveratrol, vitamin D3, 2-deoxyglucose, and acetylsalicylic acid |
| 23137030 | These DDS events are detected immunocytochemically using phospho-specific Abs; flow cytometry or image-assisted cytometry provide the means to quantitatively assess them on a cell by cell basis |
Entries Per Page
Displaying Page of
